Tetrazole

Tetrazole

SCHEMBL9632333

CCc1c(N)ccc(-c2ccc(N)cc2)c1CC.c1nnn[nH]1

nearest known ligand 0.30

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11129444 0.82 TDP1 (0.39) USP7
Methane SCHEMBL28624868 0.81 TDP1 (0.37) USP7
Tetrazole SCHEMBL27988029 0.79 ASIC3 (0.31)
Benzidine SCHEMBL9632331 0.78 ALDH1A1 (0.39)
Tetrazole SCHEMBL9630986 0.76 MEN1 (0.38)
Benzidine SCHEMBL5132264 0.75 ALDH1A1 (0.48)
Benzidine SCHEMBL7639491 0.74 ALDH1A1 (0.46)
SCHEMBL5381204 0.73 USP7 (0.37) USP7
SCHEMBL5382796 0.71 SKP2 (0.40) USP7
SCHEMBL5386508 0.70 RPS6KA3 (0.38) USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5134057-A METHOD OF PROVIDING A SUBSTRATE WITH A LAYER COMPRISING A POLYVINYL BASED HYDROGEL AND A BIOCHEMICALLY ACTIVE MATERIAL 501 PPG BIOMEDICAL SYSTEMS, INC. (US) 1992-07-28 US claimed
EP-0363504-A1 Method of providing a substrate with a layer comprising a polyvinylbased hydrogel and a biochemically active material Dräger Nederland B.V. (NL) 1990-04-18 EP claimed