Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633992 | 0.84 | KDM4E (0.52) | L3MBTL1TDP1SMN1; SMN2KMT2ACHRM2 | |
| SCHEMBL9634005 | 0.83 | L3MBTL1 (0.49) | L3MBTL1TDP1SMN1; SMN2KMT2ACHRM2 | |
| SCHEMBL2035810 | 0.80 | L3MBTL1 (0.53) | L3MBTL1TDP1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL7682704 | 0.79 | SCN8A (0.36) | L3MBTL1TDP1SMN1; SMN2HTR1ASLC6A2 | |
| SCHEMBL21246942 | 0.79 | L3MBTL1 (0.43) | L3MBTL1TDP1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL30750877 | 0.78 | SLC6A2 (0.44) | L3MBTL1TDP1KMT2AALDH1A1HTR1A | |
| SCHEMBL17393516 | 0.78 | SLC6A2 (0.44) | L3MBTL1TDP1KMT2AALDH1A1HTR1A | |
| SCHEMBL5824853 | 0.77 | L3MBTL1 (0.58) | L3MBTL1TDP1SMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL29669870 | 0.77 | NFE2L2 (0.50) | L3MBTL1TDP1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL1627720 | 0.77 | NFE2L2 (0.50) | L3MBTL1TDP1SMN1; SMN2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331943-B1 | PHENOXYETHYLAMINE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND COMPOSITION FOR EXHIBITING EXCELLENT ALPHA-1-BLOCKING ACTIVITY CONTAINING THE SAME | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1992-06-17 | — | — | EP | disclosed |
| US-4971990-A | HYPOTENSIVE AGENTS, DYSUREA | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0331943-A1 | Phenoxyethylamine derivatives, process for preparing the same, and composition for exhibiting excellent alpha-1-blocking activity containing the same | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1989-09-13 | — | — | EP | disclosed |