Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DTYMK | P23919 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM4B | O94953 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633098 | 0.90 | ALDH1A1 (0.43) | DTYMKPTPN1PTPN2PTPN6HNF4A | |
| SCHEMBL9630808 | 0.88 | DTYMK (0.60) | DTYMKPTPN1PTPN2PTPN6HNF4A | |
| SCHEMBL5594749 | 0.83 | PLA2G4A (0.50) | PTPN1SNCABACE1NPC1MAPT | |
| SCHEMBL5594752 | 0.83 | PLA2G4A (0.50) | PTPN1SNCABACE1NPC1MAPT | |
| SCHEMBL5594757 | 0.83 | PLA2G4A (0.50) | PTPN1SNCABACE1NPC1MAPT | |
| SCHEMBL9632184 | 0.80 | TUBB4A (0.40) | PTGS2SNCABACE1MAPTPOLB | |
| SCHEMBL10335465 | 0.80 | MAPT (0.45) | BACE1NPC1MAPTRAB9ATSHR | |
| SCHEMBL9632156 | 0.78 | ALDH1A1 (0.42) | DTYMKPTPN1PTPN2PTPN6HNF4A | |
| SCHEMBL6824218 | 0.77 | BACE1 (0.50) | PTPN1SNCABACE1MAPTTSHR | |
| SCHEMBL7288138 | 0.77 | ALDH5A1 (0.57) | MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359795-B1 | ZWITTERION NLO-CHROMOPHORES | MERCK PATENT GmbH (DE) | 1992-04-15 | — | — | EP | disclosed |
| EP-0359795-A1 | ZWITTERION NLO-CHROMOPHORES. | MERCK PATENT GMBH (DE) | 1990-03-28 | — | — | EP | disclosed |
| WO-1989008686-A1 | ZWITTERION NLO-CHROMOPHORES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-09-21 | — | — | WO | disclosed |