Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633919 | 0.74 | OPRM1 (0.32) | — | |
| SCHEMBL993153 | 0.73 | — | — | |
| SCHEMBL6204520 | 0.69 | PER2 (0.33) | SIGMAR1 | |
| SCHEMBL993043 | 0.67 | — | — | |
| SCHEMBL2819250 | 0.67 | — | — | |
| SCHEMBL7558118 | 0.67 | — | — | |
| SCHEMBL11221601 | 0.65 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL5620733 | 0.63 | ALDH1A1 (0.36) | — | |
| SCHEMBL2187185 | 0.63 | CYP3A4 (0.35) | — | |
| SCHEMBL5621142 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162523-A | CEPHALOSPORIN ANTIBACTERIAL COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 1992-11-10 | — | — | US | disclosed |
| US-5159077-A | Bactericide, antibiotic | HOFFMANN-LA ROCHE INC. (US) | 1992-10-27 | — | — | US | disclosed |
| EP-0409081-A1 | Beta-Lactam Derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-01-23 | — | — | EP | disclosed |
| US-4670553-A | 2-oxo-1-(aminocarbonylaminosulfonyl-aminocarbonyl)azetidines | E. R. SQUIBB & SONS, INC. (US) | 1987-06-02 | — | — | US | disclosed |
| EP-0085291-A1 | 2-Oxo-1-(aminocarbonylaminosulfonylaminocarbonyl)azetidines | E.R. Squibb & Sons, Inc. (US) | 1983-08-10 | — | — | EP | disclosed |