Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | MGLL | Q99685 | 2/20 | 0.62 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | GABRD | O14764 | 1/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.56 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.56 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | UBE2M | P61081 | 1/20 | 0.55 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.55 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8054515 | 0.86 | HPGD (0.69) | HPGDMGLLHSD11B1EPHX2L3MBTL1 | |
| SCHEMBL12977 | 0.86 | HPGD (0.69) | HPGDMGLLHSD11B1EPHX2L3MBTL1 | |
| SCHEMBL14238822 | 0.85 | HPGD (0.83) | HPGDMGLLHSD11B1L3MBTL1HTT | |
| SCHEMBL7130857 | 0.85 | HPGD (0.83) | HPGDMGLLHSD11B1L3MBTL1HTT | |
| SCHEMBL23417312 | 0.85 | HPGD (0.68) | HPGDMGLLHSD11B1EPHX2L3MBTL1 | |
| SCHEMBL14255587 | 0.84 | MGLL (0.68) | HPGDMGLLHSD11B1EPHX2L3MBTL1 | |
| SCHEMBL12976 | 0.82 | HPGD (0.64) | HPGDMGLLHSD11B1EPHX2L3MBTL1 | |
| SCHEMBL23417314 | 0.82 | HPGD (0.64) | HPGDMGLLHSD11B1EPHX2L3MBTL1 | |
| SCHEMBL9633280 | 0.82 | HPGD (0.64) | HPGDMGLLHSD11B1EPHX2L3MBTL1 | |
| SCHEMBL14003455 | 0.82 | HPGD (0.64) | HPGDMGLLHSD11B1EPHX2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5096900-A | Antidepressants, anxiolytic agents | SYNTHELABO (FR) | 1992-03-17 | — | — | US | disclosed |
| US-5081128-A | Antidepressants, anxiolytic agents | SYNTHELABO (FR) | 1992-01-14 | — | — | US | disclosed |