Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | FDPS | P14324 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634035 | 1.00 | ALOX15 (0.52) | ALOX15ALDH1A1FDPS | |
| SCHEMBL9633712 | 0.84 | FDPS (0.57) | FDPS | |
| SCHEMBL9702817 | 0.83 | FDPS (0.54) | FDPS | |
| SCHEMBL8622489 | 0.80 | ALOX15 (0.45) | ALOX15ALDH1A1 | |
| SCHEMBL9633364 | 0.77 | — | — | |
| SCHEMBL9632023 | 0.77 | — | — | |
| SCHEMBL9633372 | 0.77 | — | — | |
| SCHEMBL9632034 | 0.77 | — | — | |
| SCHEMBL9128774 | 0.76 | FDPS (0.47) | FDPS | |
| SCHEMBL9633361 | 0.76 | LMNA (0.58) | ALOX15FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513761-A2 | Bisphosphonate squalene synthetase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1992-11-19 | — | — | EP | claimed |
| EP-0513761-A2 | Bisphosphonate squalene synthetase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1992-11-19 | — | — | EP | disclosed |
| US-5157027-A | Anticholesterol agents | E. R. SQUIBB & SONS, INC. (US) | 1992-10-20 | — | — | US | disclosed |