Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10619690 | 0.78 | SHBG (0.31) | SHBG | |
| SCHEMBL5897753 | 0.74 | NR3C1 (0.38) | SHBG | |
| SCHEMBL978478 | 0.73 | SHBG (0.36) | SHBG | |
| SCHEMBL9622775 | 0.71 | ABCB11 (0.39) | SHBG | |
| SCHEMBL5331450 | 0.70 | SHBG (0.52) | SHBG | |
| SCHEMBL2532842 | 0.67 | — | — | |
| SCHEMBL6272318 | 0.67 | HSD17B1 (0.44) | SHBG | |
| SCHEMBL5470756 | 0.65 | CYP19A1 (0.39) | — | |
| SCHEMBL11639279 | 0.65 | CYP19A1 (0.43) | — | |
| SCHEMBL11313520 | 0.63 | CYP19A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298020-B1 | USE OF AN EPOXIDATION REAGENT, AND PROCESS FOR THE PREPARATION OF 5-ALPHA (10-ALPHA) EPOXY-DELTA 9(11) STEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-06-24 | — | — | EP | disclosed |
| US-4900725-A | CONTRACEPTIVES | ROUSSEL UCLAF (FR) | 1990-02-13 | — | — | US | disclosed |
| EP-0135400-B1 | ESTRADIENE DERIVATIVES LABELLED WITH TRITIUM, THEIR PREPARATION AND INTERMEDIATES FOR THEIR PREPARATION, AND THEIR UTILIZATION IN THE STUDY AND IN THE DETERMINATION OF STEROIDS IN BIOLOGICAL FLUIDS | ROUSSEL-UCLAF (FR) | 1988-06-01 | — | — | EP | disclosed |