SCHEMBL963479

SCHEMBL963479

CO[Si](CCCC(=O)NN)(OC)OC

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.45
GAA P10253 1/20 0.42
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 2/20 0.40
KDM5C P41229 1/20 0.40
PHF8 Q9UPP1 1/20 0.40
KDM2A Q9Y2K7 1/20 0.40
RECQL P46063 1/20 0.39
TSHR P16473 2/20 0.37
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C19 P33261 1/20 0.35
LMNA P02545 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
POLB P06746 1/20 0.33
HTT P42858 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL553701 0.88 CTSD (0.48) CTSDGAAALDH1A1KDM4EKDM5C
SCHEMBL27494535 0.82 RECQL (0.41) GAAALDH1A1RECQLTSHRLMNA
SCHEMBL962708 0.81 CTSD (0.47) CTSDGAAALDH1A1KDM4EKDM5C
SCHEMBL27628884 0.79 TSHR (0.46) RECQLTSHRPOLB
SCHEMBL27516755 0.79 LMNA (0.35) KDM4ERECQLTSHRCYP1A2CYP3A4
SCHEMBL1188812 0.77 RECQL (0.41) GAAALDH1A1RECQLTSHRLMNA
SCHEMBL6228812 0.77 TSHR (0.61) GAAALDH1A1KDM4ERECQLTSHR
SCHEMBL18164189 0.76 TSHR (0.55) RECQLTSHRPOLB
SCHEMBL7601892 0.76 TSHR (0.50) RECQLTSHRLMNAL3MBTL1POLB
SCHEMBL27805033 0.76 CASP2 (0.52) TSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2248833-B1 MODIFIED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION USING THE SAME, AND TIRE BRIDGESTONE CORP (JP) 2014-03-26 EP disclosed
US-20130289165-A1 COMPOSITION BASED ON NATURAL RUBBER AND CARBON BLACK COMPRISING A HYDRAZIDE, A HYDRAZONE AND A POLYAMINE MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2013-10-31 US disclosed
EP-2655495-A1 COMPOSITION BASED ON NATURAL RUBBER AND CARBON BLACK COMPRISING A HYDRAZIDE, A HYDRAZONE AND A POLYAMINE Compagnie Générale des Etablissements Michelin (FR) 2013-10-30 EP disclosed
US-8389641-B2 Modified diene rubber, production method thereof, and rubber composition and tire using the rubber BRIDGESTONE CORPORATION (JP) 2013-03-05 US disclosed
US-8288152-B2 Semiconductor nanocrystal probes for biological applications and process for making and using such probes THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-10-16 US disclosed
US-8288153-B2 Semiconductor nanocrystal probes for biological applications and process for making and using such probes THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-10-16 US disclosed
WO-2012084821-A1 COMPOSITION BASED ON NATURAL RUBBER AND CARBON BLACK COMPRISING A HYDRAZIDE, A HYDRAZONE AND A POLYAMINE COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2012-06-28 WO disclosed
US-20110003911-A1 MODIFIED DIENE RUBBER, PRODUCTION METHOD THEREOF, AND RUBBER COMPOSITION AND TIRE USING THE RUBBER BRIDGESTONE CORPORATION (JP) 2011-01-06 US disclosed
EP-2248833-A1 MODIFIED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION USING THE SAME, AND TIRE Bridgestone Corporation (JP) 2010-11-10 EP disclosed
US-20100249336-A1 MODIFIED NATURAL RUBBER AND METHOD FOR PRODUCING SAME, AND RUBBER COMPOSITION AND TIRE USING SUCH A MODIFIED NATURAL RUBBER BRIDGESTONE CORPORATION (JP) 2010-09-30 US disclosed
US-20100224853-A1 SEMICONDUCTOR NANOCRYSTAL PROBES FOR BIOLOGICAL APPLICATIONS AND PROCESS FOR MAKING AND USING SUCH PROBES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2010-09-09 US disclosed
EP-2206730-A1 MODIFIED NATURAL RUBBER, PROCESS FOR PRODUCTION OF THE SAME, AND RUBBER COMPOSITION AND TIRE EACH COMPRISING THE SAME Bridgestone Corporation (JP) 2010-07-14 EP disclosed
US-20100155668-A1 SEMICONDUCTOR NANOCRYSTAL PROBES FOR BIOLOGICAL APPLICATIONS AND PROCESS FOR MAKING AND USING SUCH PROBES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2010-06-24 US disclosed
US-20090253211-A1 SEMICONDUCTOR NANOCRYSTAL PROBES FOR BIOLOGICAL APPLICATIONS AND PROCESS FOR MAKING AND USING SUCH PROBES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2009-10-08 US disclosed
US-20090191567-A1 SEMICONDUCTOR NANOCRYSTAL PROBES FOR BIOLOGICAL APPLICATIONS AND PROCESS FOR MAKING AND USING SUCH PROBES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2009-07-30 US disclosed
US-7314764-B2 Medical and nonmedical fluorescence microscopy, histology, flow cytometry, in situ hybridization, immunoassays and nucleotide sequences separation and determination; semiconductor nanocrystal which emits light when excited; affinity molecule linked to the semiconductor nanocrystal THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-01-01 US disclosed
US-20070111350-A1 SEMICONDUCTOR NANOCRYSTAL PROBES FOR BIOLOGICAL APPLICATIONS AND PROCESS FOR MAKING AND USING SUCH PROBES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2007-05-17 US disclosed