SCHEMBL553701

SCHEMBL553701

CO[Si](CCC(=O)NN)(OC)OC

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CTSD P07339 2/20 0.48
KDM4E B2RXH2 3/20 0.43
KDM5C P41229 1/20 0.43
PHF8 Q9UPP1 1/20 0.43
KDM2A Q9Y2K7 1/20 0.43
GAA P10253 3/20 0.36
ALDH1A1 P00352 3/20 0.35
LMNA P02545 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
MAPT P10636 1/20 0.34
POLB P06746 1/20 0.34
HTT P42858 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
RECQL P46063 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL963479 0.88 CTSD (0.45) CTSDKDM4EKDM5CPHF8KDM2A
SCHEMBL963046 0.79 CTSD (0.50) CTSDKDM4EKDM5CPHF8KDM2A
SCHEMBL6037110 0.78 TSHR (0.40) ALDH1A1LMNAPOLBCYP3A4CYP2C19
SCHEMBL964969 0.77 CTSD (0.41) CTSDKDM4EKDM5CPHF8KDM2A
SCHEMBL3463747 0.75 TSHR (0.32) ALDH1A1HTTCYP1A2CYP3A4CYP2C19
SCHEMBL121146 0.75 TSHR (0.57) KDM4EGAAALDH1A1LMNAMAPT
SCHEMBL12190502 0.72 PAOX (0.50) KDM4EGAALMNAPOLBTSHR
SCHEMBL909260 0.72 TSHR (0.41) KDM5CPHF8KDM2AALDH1A1LMNA
SCHEMBL11049399 0.72 ALDH1A1 (0.45) KDM4EGAAALDH1A1LMNAMAPT
SCHEMBL28057030 0.71 CTSD (0.46) CTSDKDM4EKDM5CPHF8KDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3074415-A1 NOVEL ULTRASHORT HYDROPHOBIC PEPTIDES THAT SELF-ASSEMBLE INTO NANOFIBROUS HYDROGELS AND THEIR USES Agency For Science, Technology And Research (SG) 2016-10-05 EP claimed
WO-2015080670-A1 NOVEL ULTRASHORT HYDROPHOBIC PEPTIDES THAT SELF-ASSEMBLE INTO NANOFIBROUS HYDROGELS AND THEIR USES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2015-06-04 WO claimed
US-20070161043-A1 Methods of Preparing Multicolor Quantum Dot Tagged Beads and Conjugates Thereof ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. (US) 2007-07-12 US claimed
EP-1410031-A2 METHODS OF PREPARING MULTICOLOR QUANTUM DOT TAGGED BEADS AND CONJUGATES THEREOF ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, Inc. (US) 2004-04-21 EP claimed
US-20030148544-A1 Methods of preparing multicolor quantum dot tagged beads and conjugates thereof ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. 2003-08-07 US claimed
WO-2003003015-A2 METHODS OF PREPARING MULTICOLOR QUANTUM DOT TAGGED BEADS AND CONJUGATES THEREOF ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. (US) 2003-01-09 WO claimed
US-12011480-B2 Nanoparticle compositions for sustained therapy UTI LIMITED PARTNERSHIP (CA) 2024-06-18 US disclosed
US-20230355730-A1 METHODS FOR TREATING AUTOIMMUNE DISEASE USING BIOCOMPATIBLE BIOABSORBABLE NANOSPHERES UTI LIMITED PARTNERSHIP (CA) 2023-11-09 US disclosed
US-20230193223-A1 NUCLEOTIDE TRANSIENT BINDING FOR SEQUENCING METHODS Life Technologies Corporation 2023-06-22 US disclosed
CN-110354278-B Methods and compositions for treating inflammation UTI有限合伙公司 2023-05-02 CN disclosed
US-20220401534-A1 METHODS AND COMPOSITIONS FOR SUSTAINED IMMUNOTHERAPY UTI LIMITED PARTNERSHIP (CA) 2022-12-22 US disclosed
US-11447756-B2 Nucleotide transient binding for sequencing methods Life Technologies Corporation (US) 2022-09-20 US disclosed
US-20220211868-A1 NANOPARTICLES COMPRISING NON-CLASSICAL MHC AND USES THEREOF UTI LIMITED PARTNERSHIP (CA) 2022-07-07 US disclosed
WO-2004054923-A1 TERNARY AND QUATERNARY NANOCRYSTALS, PROCESSES FOR THEIR PRODUCTION AND USES THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2004-07-01 WO disclosed
US-6727065-B2 Methods of use of semiconductor nanocrystal probes for treating a material THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-04-27 US disclosed
EP-1410031-A2 METHODS OF PREPARING MULTICOLOR QUANTUM DOT TAGGED BEADS AND CONJUGATES THEREOF ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, Inc. (US) 2004-04-21 EP disclosed
US-20030148544-A1 Methods of preparing multicolor quantum dot tagged beads and conjugates thereof ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. 2003-08-07 US disclosed
WO-2003040024-A2 ASSAY BASED ON DOPED NANOPARTICLES BAYER TECHNOLOGY SERVICES GMBH (DE) 2003-05-15 WO disclosed
WO-2003003015-A2 METHODS OF PREPARING MULTICOLOR QUANTUM DOT TAGGED BEADS AND CONJUGATES THEREOF ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. (US) 2003-01-09 WO disclosed
US-6207392-B1 COMPOUNDS CAPABLE OF LINKING TO ONE OR MORE RECEPTIVE MOLECULES; FOR THE DETECTION OF NUCLEOTIDE SEQUENCES; FOR THE RELEASE OF TOXIC COMPOUNDS IN TARGET CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2001-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220401534-A1 METHODS AND COMPOSITIONS FOR SUSTAINED IMMUNOTHERAPY CD47, TFRC, ICOS CTSD 2799/4885KDM4E 1921/4885KDM5C 650/4885
US-12011480-B2 Nanoparticle compositions for sustained therapy CD4, CD47, MALT1 CTSD 2397/4885KDM4E 3815/4885KDM5C 3551/4885
US-20220211868-A1 NANOPARTICLES COMPRISING NON-CLASSICAL MHC AND USES THEREOF MICA, CD74, HLA-C CTSD 852/4885KDM4E 1939/4885KDM5C 1781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.