SCHEMBL9634824

SCHEMBL9634824

Cc1ccc(S(=O)(=O)c2cccc(C)c2C)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.56
RAPGEF4 Q8WZA2 1/20 0.48
KMT2A Q03164 2/20 0.47
ALDH1A1 P00352 4/20 0.47
NPSR1 Q6W5P4 3/20 0.47
MAPT P10636 2/20 0.47
HTT P42858 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
FEN1 P39748 1/20 0.44
NAMPT P43490 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
HSD11B1 P28845 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KDM4E B2RXH2 2/20 0.43
RXFP1 Q9HBX9 1/20 0.43
MEN1 O00255 1/20 0.43
BCHE P06276 1/20 0.42
ACHE P22303 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2487382 0.86 HTR6 (0.52) GAAKMT2AALDH1A1NPSR1MAPT
SCHEMBL30893040 0.84 GAA (0.60) GAARAPGEF4KMT2AALDH1A1NPSR1
SCHEMBL8964467 0.84 GAA (0.60) GAARAPGEF4KMT2AALDH1A1NPSR1
SCHEMBL28054087 0.84 MMP2 (0.51) KMT2ANPSR1SMN1; SMN2NAMPTCA1
SCHEMBL1538438 0.83 KMT2A (0.56) GAAKMT2AALDH1A1NPSR1MAPT
SCHEMBL14030962 0.82 GAA (0.58) GAARAPGEF4KMT2AALDH1A1NPSR1
SCHEMBL9683124 0.81 ALDH1A1 (0.53) GAAKMT2AALDH1A1NPSR1MAPT
SCHEMBL28887989 0.81 GAA (0.52) GAARAPGEF4KMT2AALDH1A1MAPT
SCHEMBL27713269 0.81 HTR6 (0.47) GAAKMT2AALDH1A1NPSR1MAPT
SCHEMBL11853033 0.81 GAA (0.68) GAARAPGEF4KMT2AALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4323948-A Capacitor structures with improved electrical stress capability WESTINGHOUSE ELECTRIC CORP. (US) 1982-04-06 US claimed
EP-0273724-B1 ACID GAS SCRUBBING BY COMPOSITE SOLVENT-SWOLLEN MEMBRANES BEND RESEARCH, INC. (US) 1992-06-17 EP disclosed
EP-0336535-A1 Gas separation by composite solvent-swollen membranes BEND RESEARCH, INC. (US) 1989-10-11 EP disclosed
US-4824443-A HIGHLY POLAR SOLVENT BEND RESEARCH, INC. (US) 1989-04-25 US disclosed
EP-0273724-A2 Acid gas scrubbing by composite solvent-swollen membranes BEND RESEARCH, INC. (US) 1988-07-06 EP disclosed
US-4737166-A SEPARATION OF HYDROGEN SULFIDE AND CARBON DIOXIDE FROM HYDROGEN, CARBON MONOXIDE AND HYDROCARBON GASES; SUPPORTED POLYMER BEND RESEARCH, INC. (US) 1988-04-12 US disclosed