Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.51 |
| ▸ | MMP9 | P14780 | 8/20 | 0.51 |
| ▸ | MMP12 | P39900 | 8/20 | 0.51 |
| ▸ | MMP13 | P45452 | 8/20 | 0.51 |
| ▸ | MMP14 | P50281 | 8/20 | 0.51 |
| ▸ | MMP1 | P03956 | 7/20 | 0.51 |
| ▸ | MMP8 | P22894 | 7/20 | 0.51 |
| ▸ | MMP16 | P51512 | 7/20 | 0.51 |
| ▸ | MMP3 | P08254 | 7/20 | 0.50 |
| ▸ | HTR6 | P50406 | 5/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL11199366 | 0.89 | KMT2A (0.49) | MMP2MMP9MMP12MMP13MMP14 | |
| SCHEMBL2487382 | 0.89 | HTR6 (0.52) | HTR6HSD11B1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL28053976 | 0.87 | MMP1 (0.55) | MMP2MMP9MMP12MMP13MMP14 | |
| SCHEMBL27713269 | 0.84 | HTR6 (0.47) | HTR6HSD11B1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9634824 | 0.84 | GAA (0.56) | HSD11B1KMT2ACA1CA2SMN1; SMN2 | |
| SCHEMBL20198343 | 0.82 | HSD11B1 (0.54) | MMP2MMP9MMP12MMP13MMP14 | |
| SCHEMBL1538438 | 0.79 | KMT2A (0.56) | HSD11B1KMT2ACA1CA2CA9 | |
| SCHEMBL9634830 | 0.77 | KMT2A (0.51) | HSD11B1KMT2ALMNANPSR1 | |
| SCHEMBL9683124 | 0.77 | ALDH1A1 (0.53) | HSD11B1KMT2ALMNASMN1; SMN2NPSR1 | |
| SCHEMBL9843289 | 0.76 | MMP1 (0.50) | MMP2MMP9MMP12MMP13MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377953-A | Polyarylene ether sulfone (PAES) polymers | SOLVAY SPECIALTY POLYMERS USA | 2016-03-02 | — | — | CN | disclosed |