Biphenyl

Biphenyl

SCHEMBL11199366

Cc1cccc(S(=O)(=O)c2cccc(C)c2C)c1C.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.49
KDM4E B2RXH2 3/20 0.43
POLB P06746 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
GAA P10253 2/20 0.39
ALDH1A1 P00352 3/20 0.38
MMP1 P03956 2/20 0.38
MMP2 P08253 2/20 0.38
MMP9 P14780 2/20 0.38
MMP8 P22894 2/20 0.38
MMP12 P39900 2/20 0.38
MMP13 P45452 2/20 0.38
MMP14 P50281 2/20 0.38
MMP16 P51512 2/20 0.38
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1538438 0.89 KMT2A (0.56) KMT2AKDM4EKEAP1NFE2L2GAA
SCHEMBL28054087 0.89 MMP2 (0.51) KMT2AMMP1MMP2MMP9MMP8
SCHEMBL9634830 0.88 KMT2A (0.51) KMT2AKDM4EPOLBCYP3A4CYP2C9
SCHEMBL2487382 0.84 HTR6 (0.52) KMT2AKDM4EPOLBGAAALDH1A1
SCHEMBL4142033 0.80 CASP1 (0.49) KDM4EPOLBCYP3A4CYP2C9GAA
SCHEMBL11225423 0.79 CA1 (0.52) KMT2AKDM4EALDH1A1HTR6CA1
SCHEMBL27713269 0.79 HTR6 (0.47) KMT2AKDM4EPOLBGAAALDH1A1
Biphenyl SCHEMBL4006535 0.78 ALDH1A1 (0.53) KMT2ACYP3A4CYP2C9KEAP1NFE2L2
Biphenyl SCHEMBL1782043 0.76 ALDH1A1 (0.45) KMT2AKDM4EPOLBCYP3A4CYP2C9
SCHEMBL7896751 0.76 KMT2A (0.47) KMT2AKEAP1NFE2L2GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681933-B1 POLYMER-METAL JUNCTION SOLVAY SPECIALTY POLYMERS USA (US) 2024-05-15 EP disclosed
US-11359120-B2 Polymer-metal junction SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2022-06-14 US disclosed
US-20210122953-A1 POLYMER-METAL JUNCTION SOLVAY SPECIALITY POLYMERS USA, LLC 2021-04-29 US disclosed
EP-3681933-A1 POLYMER-METAL JUNCTION Solvay Specialty Polymers USA, LLC (US) 2020-07-22 EP disclosed
WO-2019053164-A1 POLYMER-METAL JUNCTION SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2019-03-21 WO disclosed
US-20180282483-A1 Polyarylene ether sulfone (PAES) Polymers and Methods for Making the Same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2018-10-04 US disclosed
US-9868825-B2 Polyarylene ether sulfone (PAES) polymers SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2018-01-16 US disclosed
EP-3215487-A1 POLYARYLENE ETHER SULFONE (PAES) POLYMERS AND METHODS FOR MAKING THE SAME Solvay Specialty Polymers USA, LLC. (US) 2017-09-13 EP disclosed
US-9611361-B2 Polyarylene ether sulfone (PAES) compositions SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-04-04 US disclosed
US-20170022322-A1 New polymeric materials SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-01-26 US disclosed
WO-2016102277-A1 METHODS FOR MAKING POLYARYLENE ETHER SULFONE (PAES) POLYMERS WITH SILYLATED TERPHENYL COMPOUNDS SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-06-30 WO disclosed
WO-2016071088-A1 POLYARYLENE ETHER SULFONE (PAES) POLYMERS AND METHODS FOR MAKING THE SAME SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-05-12 WO disclosed
US-20160090450-A1 Polyarylene ether sulfone (PAES) polymers SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-03-31 US disclosed
US-20160083523-A1 Polyarylene ether sulfone (PAES) compositions SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-03-24 US disclosed
EP-2994498-A2 POLYARYLENE ETHER SULFONE (PAES) POLYMERS Solvay Specialty Polymers USA, L.L.C. (US) 2016-03-16 EP disclosed
EP-2994500-A1 POLYARYLENE ETHER SULFONE (PAES) COMPOSITIONS Solvay Specialty Polymers USA, LLC. (US) 2016-03-16 EP disclosed
WO-2015110477-A1 NEW POLYMERIC MATERIALS SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2015-07-30 WO disclosed
EP-0068695-A1 Blends of poly (parabanic acids) with other polymers EXXON RESEARCH AND ENGINEERING COMPANY (US) 1983-01-05 EP disclosed
EP-0057104-A2 Polymers containing 1,3-imidazolidine-1,3-diyl rings plasticized with aromatic sulfones or sulfoxides EXXON RESEARCH AND ENGINEERING COMPANY (US) 1982-08-04 EP disclosed
US-4325860-A Polymers characterized by 1,3-imidazolidine-1,3-diyl rings plasticized with aromatic sulfones or aromatic sulfoxides EXXON RESEARCH & ENGINEERING CO. (US) 1982-04-20 US disclosed