Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636997 | 0.75 | HTR7 (0.53) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9635366 | 0.75 | — | — | |
| SCHEMBL9636951 | 0.75 | ACHE (0.55) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9635472 | 0.72 | HTR7 (0.52) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9635385 | 0.72 | HTR1A (0.49) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9635270 | 0.72 | HTR7 (0.48) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9636954 | 0.71 | HTR1A (0.49) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9635346 | 0.71 | — | — | |
| SCHEMBL9636846 | 0.71 | HTR1A (0.49) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9872838 | 0.70 | HTR7 (0.54) | HTR7HTR1ADRD2HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114949-A | Treating disorders associated with 5HT uptake | RHONE-POULENC SANTE (FR) | 1992-05-19 | — | — | US | disclosed |