Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 10/20 | 0.38 |
| ▸ | CA1 | P00915 | 10/20 | 0.38 |
| ▸ | CA2 | P00918 | 10/20 | 0.38 |
| ▸ | CA4 | P22748 | 10/20 | 0.38 |
| ▸ | CA7 | P43166 | 10/20 | 0.38 |
| ▸ | CA9 | Q16790 | 10/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | GRK5 | P34947 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30442903 | 0.81 | CA12 (0.47) | CA12CA1CA2CA4CA7 | |
| SCHEMBL812924 | 0.81 | CA12 (0.47) | CA12CA1CA2CA4CA7 | |
| SCHEMBL30443299 | 0.79 | CA12 (0.46) | CA12CA1CA2CA4CA7 | |
| SCHEMBL8336188 | 0.67 | CA12 (0.64) | CA12CA1CA2CA4CA7 | |
| SCHEMBL22097608 | 0.66 | ALDH1A1 (0.39) | CA12CA1CA2CA4CA7 | |
| SCHEMBL7700407 | 0.66 | CA12 (0.63) | CA12CA1CA2CA4CA7 | |
| SCHEMBL444834 | 0.64 | ALDH1A1 (0.65) | KDM4ELMNAKMT2ABCHEHSD17B10 | |
| SCHEMBL7916009 | 0.63 | SLC40A1 (0.39) | CA12CA1CA2CA4CA7 | |
| SCHEMBL6616713 | 0.63 | CA12 (0.42) | CA12CA1CA2CA4CA7 | |
| Hydrochloric Acid SCHEMBL8740411 | 0.62 | ALDH1A1 (0.61) | KDM4ELMNAKMT2ABCHEHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114949-A | Treating disorders associated with 5HT uptake | RHONE-POULENC SANTE (FR) | 1992-05-19 | — | — | US | disclosed |
| US-5036075-A | Serotonin antagonists | RHONE-POULENC SANTE (FR) | 1991-07-30 | — | — | US | disclosed |
| US-5021420-A | Antiserotonine agents; central nervous system, gastroin-testinal and cardiovascular disorders | RHONE-POULENC SANTE (FR) | 1991-06-04 | — | — | US | disclosed |