Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10586609 | 0.91 | CYP11B1 (0.48) | CYP11B1KDM1AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL4890255 | 0.91 | L3MBTL1 (0.50) | CYP11B1KDM1AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL9805327 | 0.88 | CYP11B1 (0.51) | CYP11B1KDM1AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL9805468 | 0.86 | CYP11B1 (0.49) | CYP11B1KDM1AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL10430617 | 0.83 | CYP11B1 (0.57) | CYP11B1KDM1AALDH1A1MLNRCYP1A2 | |
| SCHEMBL9743680 | 0.81 | CYP1A2 (0.38) | CYP11B1KDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL398890 | 0.81 | CYP11B1 (0.58) | CYP11B1KDM1AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7779660 | 0.80 | TSHR (0.47) | ALDH1A1CYP1A2POLBCYP3A4CYP2C9 | |
| SCHEMBL2352483 | 0.80 | TSHR (0.47) | ALDH1A1CYP1A2POLBCYP3A4CYP2C9 | |
| SCHEMBL2304494 | 0.80 | SMN1; SMN2 (0.58) | CYP11B1KDM1AL3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1066286-A | — | — | None | — | — | JP | disclosed |
| EP-0306917-B1 | A NEMATIC LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1992-06-17 | — | — | EP | disclosed |
| EP-0374849-A2 | Liquid-crystal derivatives of nitrogen-containing heterocyclic compounds as components of a liquid-crystal material, and a liquid-crystal material | PAVLJUCHENKO, Assya Iosifovna (RU) | 1990-06-27 | — | — | EP | disclosed |
| US-4917818-A | STEEP VOLTAGE TRANSMITTANCE USED IN WATCHES, ELECTRONIC CALCULATORS | CHISSO CORPORATION (JP) | 1990-04-17 | — | — | US | disclosed |
| JP-S6466286-A | NEMATIC LIQUID CRYSTAL COMPOSITION | CHISSO CORP | 1989-03-13 | — | — | JP | disclosed |