Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756366 | 0.87 | LMNA (0.39) | TSHRNFKB1CYP1A2MAOAMAOB | |
| SCHEMBL8435949 | 0.84 | TSHR (0.37) | TSHRNFKB1CYP1A2MAOAMAOB | |
| SCHEMBL8434166 | 0.84 | TSHR (0.37) | TSHRNFKB1CYP1A2MAOAMAOB | |
| SCHEMBL31457449 | 0.69 | — | — | |
| SCHEMBL2891405 | 0.67 | ACHE (0.35) | TSHRNFKB1CYP1A2MAOAMAOB | |
| SCHEMBL28654635 | 0.67 | — | — | |
| SCHEMBL6256698 | 0.66 | ALOX15 (0.41) | NFKB1CYP1A2MAOALMNACYP3A4 | |
| SCHEMBL3268098 | 0.65 | — | — | |
| SCHEMBL28765986 | 0.63 | — | — | |
| SCHEMBL1724780 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5168061-A | Pregnancy regulator | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1992-12-01 | — | — | US | disclosed |