SCHEMBL7756366

SCHEMBL7756366

NC(=O)NN(NC(N)=O)C(N)=O

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
TSHR P16473 2/20 0.39
NFKB1 P19838 2/20 0.39
CYP1A2 P05177 1/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
THPO P40225 1/20 0.39
CA2 P00918 1/20 0.39
CYP3A4 P08684 1/20 0.39
CA5A P35218 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
CA9 Q16790 1/20 0.39
CRBN Q96SW2 1/20 0.32
ALDH1A1 P00352 1/20 0.31
OR51E2 Q9H255 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8435949 0.97 TSHR (0.37) LMNATSHRNFKB1CYP1A2MAOA
SCHEMBL8434166 0.97 TSHR (0.37) LMNATSHRNFKB1CYP1A2MAOA
SCHEMBL9640867 0.87 TSHR (0.30) LMNATSHRNFKB1CYP1A2MAOA
SCHEMBL2891405 0.78 ACHE (0.35) LMNATSHRNFKB1CYP1A2MAOA
SCHEMBL6256698 0.76 ALOX15 (0.41) LMNANFKB1CYP1A2MAOACYP3A4
SCHEMBL1260075 0.71
SCHEMBL1744665 0.69
SCHEMBL8520018 0.68 LMNA (0.36) LMNACYP1A2CA2BLMPMP22
SCHEMBL8386040 0.67
SCHEMBL2034380 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024058984-A2 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING INSULIN-ASSOCIATED DISEASES MarvelBiome, Inc. (US) 2024-03-21 WO disclosed
EP-3652133-A1 MIXTURES COMPRISING AN UREASE INHIBITOR (UI) AND A NITRIFICATION INHIBITOR SUCH AS 2-(3,4-DIMETHYL-1H-PYRAZOL-1-YL)SUCCINIC ACID (DMPSA) OR 3,4-DIMETHYL PYRAZOLIUM GLYCOLATE (DMPG) BASF SE (DE) 2020-05-20 EP disclosed
WO-2019012382-A1 MIXTURES COMPRISING AN UREASE INHIBITOR (UI) AND A NITRIFICATION INHIBITOR SUCH AS 2-(3,4-DIMETHYL-1H-PYRAZOL-1-YL)SUCCINIC ACID (DMPSA) OR 3,4-DIMETHYL PYRAZOLIUM GLYCOLATE (DMPG) BASF SE (DE) 2019-01-17 WO disclosed
EP-1090059-A1 TERTIARY AMINE POLYAMIDOAMINE-EPIHALOHYDRIN POLYMERS HERCULES INCORPORATED (US) 2001-04-11 EP disclosed
EP-1062102-A1 A BOOKBINDING PROCESS National Starch and Chemical Investment Holding Corporation (US) 2000-12-27 EP disclosed
US-6111032-A REACTING TERTIARYAMINE POLYAMIDOAMINE PREPOLYMER AND AN EPIHALOHYDRIN WITH A MOLAR RATIO OF EPIHALOHYDRIN AND TERTIARY AMINE OF POLYAMIDOAMINE PREPOLYMER OF LESS THAN 1:1, PH ALKALINE 7.5 TO 9, IN PRESENCE OF NONHALIDE ACID HERCULES INCORPORATED (US) 2000-08-29 US disclosed
CN-1244801-A Sulfonylurea-glitazone synergistic combinations for diabetes WARNER LAMBERT CO (US) 2000-02-16 CN disclosed
WO-1999057175-A1 TERTIARY AMINE POLYAMIDOAMINE-EPIHALOHYDRIN POLYMERS HERCULES INCORPORATED (US) 1999-11-11 WO disclosed
WO-1999048698-A1 A BOOKBINDING PROCESS NATIONAL STARCH & CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1999-09-30 WO disclosed