Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434166 | 1.00 | TSHR (0.37) | TSHRNFKB1LMNACYP1A2MAOA | |
| SCHEMBL7756366 | 0.97 | LMNA (0.39) | TSHRNFKB1LMNACYP1A2MAOA | |
| SCHEMBL9640867 | 0.84 | TSHR (0.30) | TSHRNFKB1LMNACYP1A2MAOA | |
| SCHEMBL2891405 | 0.75 | ACHE (0.35) | TSHRNFKB1LMNACYP1A2MAOA | |
| SCHEMBL6256698 | 0.73 | ALOX15 (0.41) | NFKB1LMNACYP1A2MAOACYP3A4 | |
| SCHEMBL1260075 | 0.69 | — | — | |
| SCHEMBL27993821 | 0.69 | — | — | |
| SCHEMBL1744665 | 0.67 | — | — | |
| SCHEMBL8520018 | 0.66 | LMNA (0.36) | LMNACYP1A2CA2BLMPMP22 | |
| Hydrochloric Acid SCHEMBL27489438 | 0.65 | LMNA (0.38) | TSHRNFKB1LMNACYP1A2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922654-A | TWO OR MORE ORGANOMETALLIC COMPOUNDS WHERE THE METAL IS A TRANSITION METAL OR SEMIMETAL, OR ZINC; FOR EXAMPLE, ZINC DIALKYLDITHIOPHOSPHATE, OR NICKEL DIALKYLDITHIOCARBAMATE; HIGHER LOAD BEARING PROPERTIES, HIGH TEMPERATURE PERFORMANCE | NSK LTD. (JP) | 1999-07-13 | — | — | US | disclosed |