Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.73 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.73 |
| ▸ | HTR1A | P08908 | 1/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.73 |
| ▸ | DRD2 | P14416 | 1/20 | 0.73 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.73 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.73 |
| ▸ | CNR1 | P21554 | 1/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.73 |
| ▸ | HTR2A | P28223 | 1/20 | 0.73 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.73 |
| ▸ | MC4R | P32245 | 1/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.73 |
| ▸ | HRH1 | P35367 | 1/20 | 0.73 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.73 |
| ▸ | DRD3 | P35462 | 1/20 | 0.73 |
| ▸ | SCN1A | P35498 | 1/20 | 0.73 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.73 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Prenylamine SCHEMBL77916 | 0.85 | HTR1A (1.00) | ADRB2ADRB1HTR1AADORA3DRD2 | |
| Prenylamine SCHEMBL5053804 | 0.85 | HTR1A (1.00) | ADRB2ADRB1HTR1AADORA3DRD2 | |
| Prenylamine SCHEMBL182253 | 0.85 | HTR1A (1.00) | ADRB2ADRB1HTR1AADORA3DRD2 | |
| SCHEMBL7149115 | 0.83 | ADRB2 (0.75) | ADRB2ADRB1HTR1AADORA3DRD2 | |
| Prenylamine SCHEMBL5525021 | 0.83 | HTR1A (0.97) | ADRB2ADRB1HTR1AADORA3DRD2 | |
| SCHEMBL7937104 | 0.83 | ADRB2 (0.75) | ADRB2ADRB1HTR1AADORA3DRD2 | |
| Prenylamine SCHEMBL29389965 | 0.83 | HTR1A (0.97) | ADRB2ADRB1HTR1AADORA3DRD2 | |
| SCHEMBL7149113 | 0.83 | ADRB2 (0.75) | ADRB2ADRB1HTR1AADORA3DRD2 | |
| Prenylamine SCHEMBL10614915 | 0.82 | CYP1A2 (1.00) | ADRB2ADRB1HTR1AADORA3DRD2 | |
| SCHEMBL12312536 | 0.81 | CYP2D6 (0.54) | ADRB2ADRB1HTR1AADORA3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290122-B1 | MORPHOLINE DERIVATIVES AND THEIR USE | BEECHAM GROUP PLC (GB) | 1992-12-23 | — | — | EP | disclosed |
| US-5082840-A | Animal growth regulators | BEECHAM GROUP P.L.C. (GB) | 1992-01-21 | — | — | US | disclosed |
| US-4914202-A | FOR IMPROVING FEED EFFICIENCY IN LIVESTOCK | BEECHAM GROUP P.L.C. (GB) | 1990-04-03 | — | — | US | disclosed |
| EP-0290122-A1 | Morpholine derivatives and their use | BEECHAM GROUP PLC (GB) | 1988-11-09 | — | — | EP | disclosed |