Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | BCL9 | O00512 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641801 | 0.95 | ABCB11 (0.36) | ABCB11MAOBIGLV6-57ALOX15KMT2A | |
| SCHEMBL9641972 | 0.93 | ABCB11 (0.42) | ABCB11MAOBIGLV6-57ALOX15KMT2A | |
| SCHEMBL9642668 | 0.91 | ABCB11 (0.41) | ABCB11MAOBIGLV6-57ALOX15KMT2A | |
| SCHEMBL9642951 | 0.91 | ABCB11 (0.41) | ABCB11MAOBIGLV6-57ALOX15KMT2A | |
| SCHEMBL9642116 | 0.83 | LMNA (0.38) | ABCB11KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL9642957 | 0.83 | LMNA (0.38) | ABCB11KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL9643130 | 0.81 | ALDH1A1 (0.40) | ABCB11MAOBIGLV6-57ALOX15KMT2A | |
| SCHEMBL9643387 | 0.80 | ABCB11 (0.58) | ABCB11ALOX15KMT2AALDH1A1KDM4E | |
| SCHEMBL9713265 | 0.79 | ALOX15 (0.37) | MAOBIGLV6-57ALOX15KMT2AMEN1 | |
| SCHEMBL9641652 | 0.77 | AKR1B1 (0.43) | ABCB11ALOX15KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0215622-A2 | Naphthalene anti-psoriatic agents and process for making them | SYNTEX (U.S.A.) INC. (US) | 1987-03-25 | — | — | EP | disclosed |