Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9644107 | 0.87 | HSD17B10 (0.34) | HSD17B10ALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL9643824 | 0.87 | SMN1; SMN2 (0.36) | HSD17B10ALDH1A1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL9643784 | 0.85 | ALDH1A1 (0.36) | ALDH1A1RECQLKDM4ETLR8TSHR | |
| SCHEMBL9642897 | 0.83 | MEN1 (0.37) | ALDH1A1SMN1; SMN2MAPTRECQLKDM4E | |
| SCHEMBL10441533 | 0.81 | GABRP (0.42) | ALDH1A1MAPTRECQLKDM4EL3MBTL1 | |
| SCHEMBL3159335 | 0.81 | HSD17B10 (0.37) | HSD17B10ALDH1A1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL9643782 | 0.81 | ALDH1A1 (0.34) | ALDH1A1RECQLKDM4ETLR8TSHR | |
| SCHEMBL9642713 | 0.77 | L3MBTL1 (0.40) | ALDH1A1SMN1; SMN2MAPTRECQLL3MBTL1 | |
| SCHEMBL5553553 | 0.77 | AGTR1 (0.34) | ALDH1A1RECQLKDM4ENPC1GAA | |
| SCHEMBL9643993 | 0.76 | GABRP (0.43) | ALDH1A1MAPTKDM4EL3MBTL1TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5136042-A | PROCESS FOR THE PREPARATION OF THIAZOLECARBOXYLIC ACID CHLORIDES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-08-04 | — | — | US | disclosed |