Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9643719 | 0.98 | ALDH1A1 (0.50) | ALDH1A1HPGDTSHRHSP90AA1SMN1; SMN2 | |
| SCHEMBL20503252 | 0.88 | ALDH1A1 (0.47) | ALDH1A1HPGDTSHRHSP90AA1SMN1; SMN2 | |
| SCHEMBL20503273 | 0.86 | GPR35 (0.47) | ALDH1A1HPGDTSHRHSP90AA1SMN1; SMN2 | |
| SCHEMBL9642790 | 0.85 | ALDH1A1 (0.55) | ALDH1A1HPGDTSHRHSP90AA1SMN1; SMN2 | |
| SCHEMBL9643711 | 0.84 | ALDH1A1 (0.39) | ALDH1A1HPGDTSHRHSP90AA1SMN1; SMN2 | |
| SCHEMBL2689405 | 0.84 | IKBKB (0.43) | ALDH1A1HPGDTSHRHSP90AA1KDM4E | |
| SCHEMBL290086 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HPGDTSHRHSP90AA1SMN1; SMN2 | |
| SCHEMBL18792363 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HPGDTSHRHSP90AA1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9642771 | 0.83 | ALDH1A1 (0.53) | ALDH1A1HPGDTSHRHSP90AA1SMN1; SMN2 | |
| SCHEMBL9643784 | 0.81 | ALDH1A1 (0.36) | ALDH1A1HPGDTSHRHSP90AA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10364239-B2 | Ferroportin inhibitors | VIFOR (INTERNATIONAL) AG (CH) | 2019-07-30 | — | — | US | disclosed |
| WO-2017068090-A1 | NOVEL FERROPORTIN INHIBITORS | VIFOR (INTERNATIONAL) AG (CH) | 2017-04-27 | — | — | WO | disclosed |
| US-5136042-A | PROCESS FOR THE PREPARATION OF THIAZOLECARBOXYLIC ACID CHLORIDES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-08-04 | — | — | US | disclosed |
| EP-0377750-A1 | PROCESS FOR PREPARING THIAZOLECARBOXYLIC ACID CHLORIDES | MITSUI CHEMICALS, INC. (JP) | 1990-07-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10364239-B2 | Ferroportin inhibitors | HAMP, SLC40A1, HMOX1 | ALDH1A1 1716/4885HPGD 81/4885TSHR 2449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.