Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 10/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645652 | 0.84 | CCKBR (0.40) | CCKARCCKBRLMNACYP3A4CYP2C9 | |
| SCHEMBL9558864 | 0.83 | CCKBR (0.48) | CCKBRLMNACYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL9644811 | 0.83 | CCKAR (0.48) | CCKARCCKBRTHRBLMNACYP3A4 | |
| SCHEMBL9645565 | 0.80 | THRA (0.44) | CCKARCCKBRTHRATHRBLMNA | |
| SCHEMBL9645604 | 0.77 | CCKBR (0.44) | CCKARCCKBRLMNACYP3A4CYP2C9 | |
| SCHEMBL9558991 | 0.75 | PLA2G2A (0.42) | CCKBRLMNACYP3A4CYP2C9 | |
| SCHEMBL9646243 | 0.69 | MCHR1 (0.48) | CCKBRTHRATHRBLMNACYP3A4 | |
| SCHEMBL9646313 | 0.68 | CCKBR (0.41) | CCKARCCKBRLMNACYP3A4CYP2C9 | |
| SCHEMBL9644737 | 0.67 | THRA (0.46) | CCKARCCKBRTHRATHRB | |
| SCHEMBL2011642 | 0.66 | HPGD (0.52) | LMNACYP3A4CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508004-A1 | Phenylsulfonylalkanoic acid compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1992-10-14 | — | — | EP | disclosed |
| US-5145869-A | Treatment of irritable bowel syndrome, dyskinesia, pancreatist; hormone inhibitors | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-09-08 | — | — | US | disclosed |