Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 7/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 3/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646243 | 0.89 | MCHR1 (0.48) | THRATHRBLMNACYP3A4CYP2C9 | |
| SCHEMBL9644737 | 0.88 | THRA (0.46) | THRATHRBCCKARCCKBRMMP1 | |
| SCHEMBL9646092 | 0.84 | LMNA (0.48) | THRBLMNACYP3A4CYP2C9TSHR | |
| SCHEMBL9645573 | 0.80 | CCKAR (0.39) | THRATHRBLMNACYP3A4CYP2C9 | |
| SCHEMBL9558960 | 0.79 | CCKBR (0.46) | ALDH1A1CCKARCCKBRMMP1 | |
| SCHEMBL9559024 | 0.77 | CCKBR (0.46) | ALDH1A1CCKBRMMP1 | |
| SCHEMBL9646074 | 0.77 | CCKBR (0.44) | THRBLMNACYP3A4CYP2C9TSHR | |
| SCHEMBL9558525 | 0.76 | ALDH1A1 (0.43) | LMNAALDH1A1CCKBRMMP1 | |
| SCHEMBL9559158 | 0.76 | GAA (0.48) | LMNAALDH1A1CCKBRMMP1 | |
| SCHEMBL9558853 | 0.75 | ALDH1A1 (0.43) | LMNAALDH1A1CCKBRMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3151355-A | — | — | None | — | — | JP | disclosed |
| EP-0508004-A1 | Phenylsulfonylalkanoic acid compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1992-10-14 | — | — | EP | disclosed |
| US-5145869-A | Treatment of irritable bowel syndrome, dyskinesia, pancreatist; hormone inhibitors | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-09-08 | — | — | US | disclosed |
| JP-H03151355-A | PHENYLSULFONYLALKYLCARBOXYLIC ACID DERIVATIVE | KISSEI PHARMACEUT CO LTD | 1991-06-27 | — | — | JP | disclosed |