Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1189663 | 0.82 | ABL1 (0.68) | ALDH1A1HSD17B10HTTABL1KDM4E | |
| Hydrochloric Acid SCHEMBL8134380 | 0.81 | ABL1 (0.66) | ALDH1A1HSD17B10HTTABL1KDM4E | |
| SCHEMBL9645447 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HSD17B10KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL2896486 | 0.80 | ALDH1A1 (0.62) | ALDH1A1HSD17B10KDM4ESMN1; SMN2HPGD | |
| SCHEMBL197307 | 0.79 | TRPV1 (0.61) | ALDH1A1TRPV1KDM4EELANESMN1; SMN2 | |
| SCHEMBL29443099 | 0.79 | TRPV1 (0.61) | ALDH1A1TRPV1KDM4EELANESMN1; SMN2 | |
| SCHEMBL9645683 | 0.78 | HSD17B10 (0.49) | ALDH1A1HSD17B10KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL10597819 | 0.78 | ALDH1A1 (0.58) | ALDH1A1HSD17B10KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL559271 | 0.78 | ALDH1A1 (0.58) | ALDH1A1HSD17B10HTTKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27624411 | 0.77 | TRPV1 (0.59) | ALDH1A1TRPV1KDM4EELANESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346713-B1 | BENZAMIDINES USEFUL AS ULTRAVIOLET LIGHT ABSORBERS | L. GIVAUDAN & CIE Société Anonyme (CH) | 1992-09-16 | — | — | EP | disclosed |