Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.43 |
| ▸ | QDPR | P09417 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526384 | 0.88 | LMNA (0.50) | SERPINE1LMNAHTTACMSDSMN1; SMN2 | |
| SCHEMBL10182181 | 0.85 | LMNA (0.68) | LMNAHTTSMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL10180298 | 0.83 | LMNA (0.65) | LMNAHTTSMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL10785889 | 0.80 | LMNA (0.48) | SERPINE1LMNAHTTACMSDSMN1; SMN2 | |
| Resorcinol SCHEMBL8415130 | 0.79 | LMNA (0.50) | LMNAHTTSMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL9296645 | 0.79 | HSP90AA1 (0.58) | SERPINE1LMNAHTTACMSDKDM4E | |
| SCHEMBL9297221 | 0.79 | ACMSD (0.57) | SERPINE1LMNAHTTACMSDSMN1; SMN2 | |
| SCHEMBL8306482 | 0.78 | LMNA (0.60) | LMNAHTTSMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL68815 | 0.77 | QDPR (0.66) | SERPINE1ACMSDMEN1POLBKMT2A | |
| SCHEMBL30320261 | 0.77 | SERPINE1 (0.64) | SERPINE1KDM4EHSD17B10ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213454-B1 | HEAT SENSITIVE RECORDING SHEETS CONTAINING SULFONE DERIVATIVES | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1992-12-02 | — | — | EP | claimed |
| US-5043313-A | Mixture of leuco dye and diphenyl polyhydroxy sulfone compound | RICOH COMPANY, LTD. (JP) | 1991-08-27 | — | — | US | claimed |
| US-4729984-A | CHROMOGENS | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1988-03-08 | — | — | US | claimed |
| EP-0213454-A2 | Heat sensitive recording sheets containing sulfone derivatives | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1987-03-11 | — | — | EP | claimed |
| EP-0213454-B1 | HEAT SENSITIVE RECORDING SHEETS CONTAINING SULFONE DERIVATIVES | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1992-12-02 | — | — | EP | disclosed |
| US-5043313-A | Mixture of leuco dye and diphenyl polyhydroxy sulfone compound | RICOH COMPANY, LTD. (JP) | 1991-08-27 | — | — | US | disclosed |
| US-4729984-A | CHROMOGENS | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1988-03-08 | — | — | US | disclosed |