Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | ABAT | P80404 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9646283 | 0.98 | S1PR2 (0.43) | S1PR2S1PR1S1PR3LPAR2KDM4E | |
| SCHEMBL27508219 | 0.90 | ESR1 (0.42) | S1PR2S1PR1S1PR3LPAR2KDM4E | |
| SCHEMBL6055164 | 0.84 | S1PR2 (0.46) | S1PR2S1PR1S1PR3LPAR2KDM4E | |
| SCHEMBL9754371 | 0.82 | S1PR2 (0.44) | S1PR2S1PR1S1PR3LPAR2KDM4E | |
| SCHEMBL10659715 | 0.82 | ENPP2 (0.43) | KDM4EALDH1A1TSHRNFKB1HIF1A | |
| SCHEMBL6612632 | 0.82 | LMNA (0.56) | KDM4EABATTAAR1HTR3ATSHR | |
| SCHEMBL12982553 | 0.80 | ALDH1A1 (0.42) | S1PR2S1PR1S1PR3LPAR2KDM4E | |
| SCHEMBL29861002 | 0.79 | BDKRB2 (0.48) | S1PR2S1PR1S1PR3LPAR2KDM4E | |
| SCHEMBL9334391 | 0.79 | PTGS1 (0.49) | S1PR2S1PR1S1PR3LPAR2HTR2A | |
| SCHEMBL9334416 | 0.79 | PTGS1 (0.49) | S1PR2S1PR1S1PR3LPAR2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173496-A | Antiinflammatory agents | ICI PHARMA (FR) | 1992-12-22 | — | — | US | disclosed |
| EP-0284174-B1 | THERAPEUTIC PREPARATIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-29 | — | — | EP | disclosed |
| EP-0284174-A1 | Therapeutic preparations | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-28 | — | — | EP | disclosed |