Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646817 | 0.84 | PTAFR (0.55) | PTAFRGAA | |
| SCHEMBL9647843 | 0.81 | PTAFR (0.52) | PTAFRGAA | |
| SCHEMBL9740818 | 0.78 | ALDH1A1 (0.52) | — | |
| SCHEMBL10425283 | 0.78 | ALDH1A1 (0.52) | — | |
| SCHEMBL9647018 | 0.76 | TBXAS1 (0.59) | — | |
| SCHEMBL9646332 | 0.76 | PTAFR (0.56) | PTAFRGAA | |
| SCHEMBL9646835 | 0.76 | PTAFR (0.54) | PTAFR | |
| Hydrochloric Acid SCHEMBL9646356 | 0.76 | TBXAS1 (0.58) | — | |
| SCHEMBL9718007 | 0.73 | PTAFR (0.53) | PTAFR | |
| Hydrochloric Acid SCHEMBL9717948 | 0.73 | PTAFR (0.52) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017476-A1 | BENZOYLPHENYL PYRIDINYLTHIAZOLIDINE COMPOUNDS AS PLATELET ACTIVATING ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-10-15 | — | — | WO | disclosed |
| US-5120751-A | Platelet activating factor antagonist | ABBOTT LABORATORIES (US) | 1992-06-09 | — | — | US | disclosed |