Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15024024 | 0.92 | MAPT (0.45) | L3MBTL1PDE5APRKCZEGFRERBB2 | |
| SCHEMBL4410072 | 0.92 | MAPT (0.45) | L3MBTL1PDE5APRKCZEGFRERBB2 | |
| SCHEMBL9355980 | 0.81 | PDE5A (0.45) | PDE5AEGFRERBB2KDM4EMEN1 | |
| SCHEMBL9355978 | 0.81 | PDE5A (0.45) | PDE5AEGFRERBB2KDM4EMEN1 | |
| SCHEMBL9359540 | 0.75 | MEN1 (0.51) | L3MBTL1PDE5AEGFRERBB2KDM4E | |
| SCHEMBL9359546 | 0.75 | MEN1 (0.51) | L3MBTL1PDE5AEGFRERBB2KDM4E | |
| SCHEMBL11324793 | 0.68 | MAPT (0.41) | L3MBTL1EGFRERBB2KDM4EMEN1 | |
| SCHEMBL9649398 | 0.66 | L3MBTL1 (0.73) | L3MBTL1PRKCZEGFRERBB2MEN1 | |
| SCHEMBL2253754 | 0.66 | NFE2L2 (0.49) | KDM4EMEN1ALDH1A1LMNAGLA | |
| SCHEMBL10625250 | 0.65 | DOCK2 (0.32) | L3MBTL1KDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231835-B1 | ELECTRO PHOTOGRAPHIC RECORDING MATERIAL | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-11 | — | — | EP | disclosed |
| US-4762760-A | FILM ON SUBSTRATE, ADHESION, FLEXIBILITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0231835-A2 | Electro photographic recording material | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-08-12 | — | — | EP | disclosed |