SCHEMBL9650398

SCHEMBL9650398

OCC1CC2CC(O)C1C2

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 4/20 0.33
SI P14410 1/20 0.33
PYGL P06737 1/20 0.33
GBA2 Q9HCG7 1/20 0.33
GAA P10253 1/20 0.33
GLB1 P16278 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9650404 1.00 GBA1 (0.33) GBA1SIPYGLGBA2GAA
SCHEMBL1461057 0.84 SI (0.33) SI
SCHEMBL893299 0.84 SI (0.33) SI
SCHEMBL15923504 0.81 GLB1 (0.31) GLB1
SCHEMBL4892113 0.78 CYP2C9 (0.48)
SCHEMBL24506594 0.75
SCHEMBL1879862 0.74
SCHEMBL10733962 0.73 CYP2C9 (0.48)
SCHEMBL19604530 0.73 CYP2C9 (0.32) GBA1
SCHEMBL17723432 0.73 SI (0.41) SI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4166915-A Process for the preparation of endo-6-hydroxybicyclo[2.2.1]heptane-endo-2-methanol and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1979-09-04 US claimed
US-7989651-B2 trimethoxysilylpropyl-carbamic acid oxiranylmethyl ester; reacting glycidol with gamma-isocyanatopropyltriethoxysilane in presence of dibutyltin laurate catalyst MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-08-02 US disclosed
US-20080221238-A1 Epoxysilanes, processes for their manufacture and curable compositions containing same MOMENTIVE PERFORMANCE MATERIALS INC. 2008-09-11 US disclosed
US-5168101-A Hypotensives, anticoagulants, cardiovascular and brain disorders ONO PHARMACEUTICAL CO., LTD. (JP) 1992-12-01 US disclosed
US-4177290-A CNS ACTIVITY LABORATOIRE L. LAFON (FR) 1979-12-04 US disclosed
US-4166915-A Process for the preparation of endo-6-hydroxybicyclo[2.2.1]heptane-endo-2-methanol and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1979-09-04 US disclosed
US-4166915-A Process for the preparation of endo-6-hydroxybicyclo[2.2.1]heptane-endo-2-methanol and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1979-09-04 US disclosed