Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 4/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GLB1 | P16278 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9650398 | 1.00 | GBA1 (0.33) | GBA1SIPYGLGBA2GAA | |
| SCHEMBL1461057 | 0.84 | SI (0.33) | SI | |
| SCHEMBL893299 | 0.84 | SI (0.33) | SI | |
| SCHEMBL15923504 | 0.81 | GLB1 (0.31) | GLB1 | |
| SCHEMBL4892113 | 0.78 | CYP2C9 (0.48) | — | |
| SCHEMBL24506594 | 0.75 | — | — | |
| SCHEMBL1879862 | 0.74 | — | — | |
| SCHEMBL10733962 | 0.73 | CYP2C9 (0.48) | — | |
| SCHEMBL19604530 | 0.73 | CYP2C9 (0.32) | GBA1 | |
| SCHEMBL17723432 | 0.73 | SI (0.41) | SI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5168101-A | Hypotensives, anticoagulants, cardiovascular and brain disorders | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-12-01 | — | — | US | disclosed |