Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22560253 | 0.81 | MAPT (0.53) | TSHRALOX15NPSR1MAPTALDH1A1 | |
| SCHEMBL23222239 | 0.78 | UBE2T (0.55) | TSHRMAPTALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL2899562 | 0.78 | KDM4E (0.50) | TSHRALOX15NPSR1MAPTALDH1A1 | |
| SCHEMBL19105558 | 0.75 | LMNA (0.50) | TSHRALOX15NPSR1MAPTALDH1A1 | |
| SCHEMBL960876 | 0.75 | HTT (0.52) | TSHRALOX15NPSR1MAPTHSD17B10 | |
| SCHEMBL4762874 | 0.73 | HTT (0.50) | TSHRALOX15NPSR1MAPTHSD17B10 | |
| SCHEMBL10140275 | 0.73 | POLB (0.56) | NPSR1MAPTALDH1A1KDM4ETP53 | |
| SCHEMBL24282131 | 0.72 | MAPT (0.68) | TSHRALOX15NPSR1MAPTALDH1A1 | |
| SCHEMBL3712068 | 0.72 | RAB9A (0.67) | TSHRALOX15NPSR1MAPTALDH1A1 | |
| SCHEMBL4138642 | 0.72 | HTT (0.68) | TSHRALOX15NPSR1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250998-B1 | SKIN WHITENING AGENT AND EXTERNAL PREPARATION FOR THE SKIN | SHISEIDO CO LTD (JP) | 2016-04-13 | — | — | EP | disclosed |
| US-8563552-B2 | Whitening agent and skin external preparation | SHISEIDO COMPANY LTD. (JP) | 2013-10-22 | — | — | US | disclosed |
| CN-101938988-B | Skin whitening agent and external preparation for the skin | SHISEIDO CO LTD | 2013-06-19 | — | — | CN | disclosed |
| US-20110003817-A1 | Whitening Agent And Skin External Preparation | SHISEIDO COMPANY LTD. (JP) | 2011-01-06 | — | — | US | disclosed |
| EP-2250998-A1 | SKIN WHITENING AGENT AND EXTERNAL PREPARATION FOR THE SKIN | Shiseido Company, Ltd. (JP) | 2010-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003817-A1 | Whitening Agent And Skin External Preparation | TYR, MC1R, RTN3 | TSHR 660/4885ALOX15 510/4885NPSR1 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.