Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.64 |
| ▸ | MMP8 | P22894 | 2/20 | 0.64 |
| ▸ | MMP14 | P50281 | 2/20 | 0.64 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 3/20 | 0.41 |
| ▸ | LAP3 | P28838 | 3/20 | 0.39 |
| ▸ | ANPEP | P15144 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588591 | 0.92 | MMP2 (0.61) | MMP2MMP8MMP14SRCMMP1 | |
| SCHEMBL8161616 | 0.80 | MMP2 (0.62) | MMP2MMP8MMP14MMP1FDPS | |
| Tiludronic Acid SCHEMBL18988 | 0.78 | MMP2 (1.00) | MMP2MMP8MMP14MMP1CA12 | |
| SCHEMBL10788079 | 0.78 | MMP8 (0.66) | MMP2MMP8MMP14MMP1CA12 | |
| SCHEMBL2149971 | 0.78 | MMP2 (0.66) | MMP2MMP8MMP14MMP1FDPS | |
| SCHEMBL8589347 | 0.78 | MMP2 (0.66) | MMP2MMP8MMP14MMP1FDPS | |
| SCHEMBL7761461 | 0.78 | MMP2 (0.55) | MMP2MMP8MMP14MMP1ACP3 | |
| SCHEMBL8166949 | 0.78 | MMP2 (0.50) | MMP2MMP8MMP14FDPSALDH1A1 | |
| Tiludronic Acid SCHEMBL3628467 | 0.77 | MMP2 (0.96) | MMP2MMP8MMP14MMP1CA12 | |
| SCHEMBL26135898 | 0.77 | MMP2 (0.63) | MMP2MMP8MMP14MMP1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339237-B1 | PHENOL SUBSTITUTED GEM-DIPHOSPHONATE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1992-12-30 | — | — | EP | claimed |