SCHEMBL9652181

SCHEMBL9652181

Cc1cc(C)c(C(C)(c2ccc(O)cc2)c2ccc(O)cc2)c(C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 0.50
ESR2 Q92731 10/20 0.50
TSHR P16473 3/20 0.46
CYP3A4 P08684 2/20 0.46
LMNA P02545 1/20 0.46
TYR P14679 1/20 0.46
AR P10275 1/20 0.46
HPGD P15428 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
HTR6 P50406 1/20 0.46
ESRRG P62508 1/20 0.46
SLC6A3 Q01959 1/20 0.46
HSD17B10 Q99714 1/20 0.46
RAPGEF4 Q8WZA2 1/20 0.46
GAA P10253 2/20 0.42
POLB P06746 1/20 0.42
GFER P55789 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28394250 0.81 ESR1 (0.43) ESR1ESR2TSHRCYP3A4LMNA
SCHEMBL3645926 0.81 ESR1 (0.59) ESR1ESR2TSHRCYP3A4LMNA
SCHEMBL9171360 0.79 ESR1 (0.59) ESR1ESR2TSHRCYP3A4LMNA
SCHEMBL9651468 0.77 ESR1 (0.47) ESR1ESR2TSHRCYP3A4LMNA
SCHEMBL5674802 0.77 MEN1 (0.47) ESR1ESR2TSHRCYP3A4LMNA
SCHEMBL13815221 0.76 ESR2 (0.67) ESR1ESR2TSHRCYP3A4LMNA
SCHEMBL3143096 0.76 ESR2 (0.67) ESR1ESR2TSHRCYP3A4LMNA
SCHEMBL3655091 0.75 ESR1 (0.52) ESR1ESR2TSHRCYP3A4LMNA
SCHEMBL13609942 0.75 ESR1 (0.59) ESR1ESR2TSHRCYP3A4LMNA
SCHEMBL22335854 0.75 ESR1 (0.80) ESR1ESR2TSHRCYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5138001-A Optical disc substrates; low birefringence, heat and moisture absorption resistance, high transparency TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1992-08-11 US disclosed
EP-0415729-A2 Vinylphenyl compound, process for the production thereof, polymerizable composition containing same, and crosslinked polymer formed therefrom TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1991-03-06 EP disclosed