Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 4/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9652373 | 0.80 | ALDH1A1 (0.48) | HRH3SIGMAR1TRPV1HTR1AHTR1D | |
| SCHEMBL11242151 | 0.79 | DRD3 (0.44) | HRH3HTR6 | |
| Hydrochloric Acid SCHEMBL11237380 | 0.78 | DRD3 (0.43) | HRH3HTR6 | |
| SCHEMBL11066548 | 0.78 | DRD4 (0.60) | HRH3SIGMAR1SLC6A4KCNH2 | |
| SCHEMBL10572119 | 0.77 | HTR1A (0.57) | HRH3SIGMAR1HTR1A | |
| Hydrochloric Acid SCHEMBL11063081 | 0.77 | DRD4 (0.59) | HRH3SIGMAR1SLC6A4KCNH2 | |
| SCHEMBL11066898 | 0.77 | DRD2 (0.53) | HRH3SIGMAR1TRPV1 | |
| SCHEMBL11724685 | 0.76 | CYP1A2 (0.46) | SIGMAR1HTR1ASLC6A4 | |
| SCHEMBL10569223 | 0.76 | SIGMAR1 (0.56) | SIGMAR1HTR1A | |
| SCHEMBL10570155 | 0.76 | HTR1A (0.57) | HRH3SIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467325-A2 | Carbostyril derivatives | SYNTEX (U.S.A.) INC. (US) | 1992-01-22 | — | — | EP | disclosed |
| US-5082847-A | Antiarrhythmia | SYNTEX (U.S.A.) INC. (US) | 1992-01-21 | — | — | US | disclosed |