Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9796885 | 0.85 | ESR1 (0.66) | LMNANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL9797446 | 0.83 | LMNA (0.67) | LMNANPC1RAB9AALDH1A1GAA | |
| SCHEMBL31152331 | 0.83 | LMNA (0.62) | LMNANPC1RAB9AALDH1A1GAA | |
| Benzoic Acid Dimethylcarbamoylmethyl Ester SCHEMBL9651513 | 0.82 | NPC1 (0.56) | LMNANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL9651207 | 0.81 | ALDH1A1 (0.50) | LMNANPC1RAB9AALDH1A1KDM4E | |
| Ethyl Benzoate SCHEMBL25388294 | 0.79 | LMNA (0.70) | LMNANPC1RAB9AALDH1A1GAA | |
| Ethyl Benzoate SCHEMBL55674 | 0.79 | LMNA (0.70) | LMNANPC1RAB9AALDH1A1GAA | |
| Ethyl Benzoate SCHEMBL2762273 | 0.79 | LMNA (0.70) | LMNANPC1RAB9AALDH1A1GAA | |
| SCHEMBL13445453 | 0.79 | NPC1 (0.60) | LMNANPC1RAB9AALDH1A1KDM4E | |
| Ethyl Benzoate SCHEMBL2451972 | 0.79 | SMN1; SMN2 (0.59) | LMNANPC1RAB9AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278977-B1 | PRODRUG DERIVATIVES OF CARBOXYLIC ACID DRUGS | Bundgaard, Hans (DK) | 1992-05-06 | — | — | EP | disclosed |
| US-5073641-A | PRODRUG DERIVATIVES OF CARBOXYLIC ACID DRUGS | BUNDGAARD HANS (DK) | 1991-12-17 | — | — | US | disclosed |
| EP-0278977-A1 | PRODRUG DERIVATIVES OF CARBOXYLIC ACID DRUGS. | BUNDGAARD HANS (DK) | 1988-08-24 | — | — | EP | disclosed |
| WO-1988001615-A1 | PRODRUG DERIVATIVES OF CARBOXYLIC ACID DRUGS | BUNDGAARD HANS (DK) | 1988-03-10 | — | — | WO | disclosed |