SCHEMBL9653192

SCHEMBL9653192

CS(=O)(=O)c1c[c]c([N+](=O)[O-])cc1Cl

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 7/20 0.33
CCR2 P41597 2/20 0.33
ALDH1A1 P00352 5/20 0.32
TSHR P16473 2/20 0.32
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
LMNA P02545 2/20 0.32
HSD11B1 P28845 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2208121 0.76 HSD17B10 (0.42) VCAM1ALDH1A1TSHRGRIN2DGRIN3B
SCHEMBL9653201 0.75 ALDH1A1 (0.36) ALDH1A1TSHRGRIN2DGRIN3BGRIN1
SCHEMBL27660498 0.75 CA1 (0.34) VCAM1ALDH1A1TSHRHSD11B1MEN1
SCHEMBL1097954 0.72 CCR2 (0.36) CCR2ALDH1A1
SCHEMBL27684781 0.72 ALDH1A1 (0.36) VCAM1ALDH1A1TSHRLMNAMEN1
SCHEMBL9653355 0.71 MAPT (0.40) ALDH1A1LMNAMEN1KMT2ACYP1A2
SCHEMBL1625901 0.70 VCAM1 (0.46) VCAM1CCR2ALDH1A1TSHRLMNA
SCHEMBL6282528 0.69 TSHR (0.42) VCAM1ALDH1A1TSHR
SCHEMBL18493453 0.68
SCHEMBL28774035 0.68 ALDH1A1 (0.36) VCAM1ALDH1A1TSHRLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0213892-B1 HERBICIDALLY ACTIVE ENOLS ROHM AND HAAS COMPANY (US) 1992-03-25 EP disclosed
US-4781750-A Herbicidally active enols ROHM AND HAAS COMPANY (US) 1988-11-01 US disclosed
EP-0213892-A2 Herbicidally active enols ROHM AND HAAS COMPANY (US) 1987-03-11 EP disclosed