SCHEMBL9654083

SCHEMBL9654083

c1cc2n(c1)-c1ccsc1CNC2

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9671934 0.80 LMNA (0.32)
SCHEMBL7305063 0.76 LMNA (0.31)
SCHEMBL3458513 0.71 SMN1; SMN2 (0.46) PNMT
SCHEMBL18838970 0.68 IKBKB (0.32)
SCHEMBL17267380 0.64 ALDH1A1 (0.43)
SCHEMBL9619222 0.62 POLB (0.30)
SCHEMBL2731241 0.62 BRPF1 (0.44)
SCHEMBL1025859 0.61
SCHEMBL15231171 0.59
SCHEMBL8128105 0.58 DRD2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5130301-A Treatment of hypoxia, antiischemic disorders and metabolic disorders ADIR ET COMPAGNIE (FR) 1992-07-14 US claimed
US-5130301-A Treatment of hypoxia, antiischemic disorders and metabolic disorders ADIR ET COMPAGNIE (FR) 1992-07-14 US disclosed