SCHEMBL9655541

SCHEMBL9655541

COC(=O)C(C)Oc1cc(N2C(=O)CC(=C(C)C)C2=O)ccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.42
MAPT P10636 4/20 0.42
KDM4E B2RXH2 2/20 0.42
LMNA P02545 2/20 0.38
HTT P42858 1/20 0.38
MEN1 O00255 5/20 0.35
KMT2A Q03164 5/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GAA P10253 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
ALOX12 P18054 1/20 0.34
HPGD P15428 3/20 0.34
PPOX P50336 1/20 0.33
F9 P00740 1/20 0.33
PLAU P00749 1/20 0.33
USP2 O75604 1/20 0.33
TSHR P16473 2/20 0.32
NOTUM Q6P988 1/20 0.32
MAPK1 P28482 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9655607 0.90 PPOX (0.44) ALDH1A1MAPTKDM4ELMNAHTT
SCHEMBL9656338 0.87 ALDH1A1 (0.39) ALDH1A1MAPTKDM4ELMNAHTT
SCHEMBL9656139 0.85 PPOX (0.40) ALDH1A1MAPTKDM4EHTTMEN1
SCHEMBL9653027 0.83 RXRA (0.38) ALDH1A1MAPTKDM4E
SCHEMBL9655555 0.83 LMNA (0.45) ALDH1A1MAPTKDM4ELMNAHTT
SCHEMBL9655645 0.83 PTGDR (0.39) ALDH1A1MAPTKDM4ELMNAMEN1
SCHEMBL9655570 0.82 ALDH1A1 (0.35) ALDH1A1MAPTKDM4ELMNAHTT
SCHEMBL9656287 0.82 ALDH1A1 (0.37) ALDH1A1MAPTKDM4ELMNAHTT
SCHEMBL9655624 0.81 PPOX (0.51) ALDH1A1KDM4ELMNAHTTGAA
SCHEMBL9656142 0.81 RORC (0.42) ALDH1A1MAPTKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0190755-B1 AN N-SUBSTITUTED-PHENYLTERACONIMIDE COMPOUND, HERBICIDAL COMPOSITION, AND METHOD FOR THE DESTRUCTION OF UNDESIRABLE WEEDS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1992-06-17 EP disclosed
US-4964905-A N-substituted-phenylteraconimide compound, herbicidal composition, and method for the destruction of undesirable weeds ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1990-10-23 US disclosed
EP-0190755-A2 An n-substituted-phenylteraconimide compound, herbicidal composition, and method for the destruction of undesirable weeds Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-08-13 EP disclosed