Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 9/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 12/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL645648 | 0.77 | POLB (0.68) | LMNARAB9AKDM4EPOLBALDH1A1 | |
| SCHEMBL645577 | 0.77 | ALDH1A1 (0.60) | LMNARAB9AKDM4EPOLBALDH1A1 | |
| SCHEMBL9653627 | 0.77 | KDM4E (0.81) | LMNARAB9AKDM4EPOLBALDH1A1 | |
| SCHEMBL9653626 | 0.77 | KDM4E (0.81) | LMNARAB9AKDM4EPOLBALDH1A1 | |
| SCHEMBL11337955 | 0.71 | RAB9A (0.62) | LMNARAB9AKDM4EPOLBALDH1A1 | |
| SCHEMBL11337959 | 0.71 | RAB9A (0.62) | LMNARAB9AKDM4EPOLBALDH1A1 | |
| SCHEMBL15765106 | 0.71 | RXRA (0.72) | LMNARAB9AKDM4EPOLBALDH1A1 | |
| SCHEMBL18656902 | 0.71 | ALDH1A1 (0.55) | LMNARAB9AKDM4EPOLBALDH1A1 | |
| SCHEMBL5857932 | 0.70 | ALDH1A1 (0.58) | LMNARAB9AKDM4EPOLBALDH1A1 | |
| SCHEMBL21225513 | 0.70 | MAPT (0.50) | LMNARAB9AKDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299974-B1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1992-01-22 | — | — | EP | claimed |
| EP-0299974-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS. | UPJOHN CO (US) | 1989-01-25 | — | — | EP | claimed |
| WO-1987006127-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-10-22 | — | — | WO | claimed |