Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9658440 | 0.88 | RAB9A (0.52) | FAAHALDH1A1RAB9AHPGDMAPT | |
| SCHEMBL9659430 | 0.85 | FAAH (0.45) | FAAHALDH1A1RAB9AHPGDMAPT | |
| SCHEMBL9656310 | 0.84 | FAAH (0.46) | FAAHALDH1A1RAB9AHPGDMAPT | |
| SCHEMBL9659077 | 0.84 | FAAH (0.46) | FAAHALDH1A1RAB9AHPGDMAPT | |
| SCHEMBL9658262 | 0.84 | ALDH1A1 (0.46) | ALDH1A1RAB9AGAANPC1LMNA | |
| SCHEMBL9656504 | 0.81 | FAAH (0.50) | FAAHRAB9AMEN1KMT2AGAA | |
| SCHEMBL9656286 | 0.81 | EPHX1 (0.43) | FAAHALDH1A1RAB9AMAPTMEN1 | |
| SCHEMBL9654984 | 0.80 | ALDH1A1 (0.61) | ALDH1A1RAB9AHPGDMAPTMEN1 | |
| SCHEMBL11040076 | 0.79 | NPSR1 (0.59) | FAAHALDH1A1RAB9AHPGDMAPT | |
| SCHEMBL9658242 | 0.79 | NCEH1 (0.53) | HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |