SCHEMBL11040076

SCHEMBL11040076

CCCOc1ccccc1OC(=O)Nc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.59
FAAH O00519 13/20 0.56
RAB9A P51151 2/20 0.52
NPC1 O15118 1/20 0.52
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
ALDH1A1 P00352 1/20 0.52
MAPT P10636 1/20 0.52
THRB P10828 1/20 0.52
HPGD P15428 1/20 0.52
ATM Q13315 1/20 0.51
KDM4E B2RXH2 1/20 0.51
GAA P10253 1/20 0.51
BLM P54132 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8341436 0.83 ALDH1A1 (0.57) NPSR1FAAHRAB9ANPC1KMT2A
SCHEMBL9656310 0.82 FAAH (0.46) NPSR1FAAHRAB9AKMT2AMEN1
SCHEMBL9659077 0.82 FAAH (0.46) NPSR1FAAHRAB9AKMT2AMEN1
SCHEMBL9874009 0.80 LMNA (0.50) NPSR1RAB9ANPC1KMT2AMEN1
SCHEMBL11038164 0.80 LMNA (0.47) NPSR1FAAHRAB9ANPC1KMT2A
SCHEMBL9659430 0.80 FAAH (0.45) NPSR1FAAHRAB9ANPC1KMT2A
SCHEMBL25271584 0.80 RAB9A (0.60) NPSR1FAAHRAB9AKMT2AALDH1A1
SCHEMBL9657252 0.79 FAAH (0.50) NPSR1FAAHRAB9ANPC1KMT2A
SCHEMBL31527768 0.79 ATM (0.77) NPSR1FAAHRAB9ANPC1KMT2A
SCHEMBL29233128 0.79 RAB9A (0.52) NPSR1FAAHRAB9AKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0121532-A1 PRODUCTION OF PHENYL CARBAMATES STAVELEY CHEMICALS (HOLDINGS) LIMITED (GB) 1984-10-17 EP disclosed
WO-1984001380-A1 PRODUCTION OF PHENYL CARBAMATES STAVELEY CHEM LTD (GB) 1984-04-12 WO disclosed