Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656286 | 0.85 | EPHX1 (0.43) | ALDH1A1NPC1RAB9AMAOB | |
| SCHEMBL9659348 | 0.84 | ALDH1A1 (0.44) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9657252 | 0.84 | FAAH (0.50) | ALDH1A1GAANPC1RAB9ALMNA | |
| SCHEMBL9659865 | 0.83 | ALDH1A1 (0.47) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9658242 | 0.82 | NCEH1 (0.53) | ACHE | |
| SCHEMBL9659126 | 0.81 | ALDH1A1 (0.45) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9659895 | 0.81 | SLC2A1 (0.42) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9641928 | 0.81 | ELANE (0.41) | ALDH1A1CCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL9656373 | 0.80 | MGLL (0.51) | ALDH1A1 | |
| SCHEMBL9658008 | 0.79 | ALDH1A1 (0.46) | ALDH1A1GAAHSD17B10CCNB2CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |