SCHEMBL965742

SCHEMBL965742

CCCCNCC(O)CCCC

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
ALDH1A1 P00352 4/20 0.41
CYP3A4 P08684 1/20 0.41
ANPEP P15144 1/20 0.39
ERAP2 Q6P179 1/20 0.39
GPR84 Q9NQS5 5/20 0.36
KDM4E B2RXH2 2/20 0.35
PKM P14618 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
FFAR1 O14842 1/20 0.35
FAAH O00519 1/20 0.35
ADH1B P00325 1/20 0.34
ADH1C P00326 1/20 0.34
ADH1A P07327 1/20 0.34
ADH7 P40394 1/20 0.34
NFKB1 P19838 1/20 0.34
DPP7 Q9UHL4 1/20 0.33
SLC15A1 P46059 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19921562 0.93 TSHR (0.50) TSHRALDH1A1CYP3A4ANPEPERAP2
SCHEMBL964318 0.91 GPR84 (0.47) TSHRALDH1A1ANPEPERAP2GPR84
SCHEMBL1270912 0.91 GPR84 (0.47) TSHRALDH1A1ANPEPERAP2GPR84
SCHEMBL965364 0.91 GPR84 (0.47) TSHRALDH1A1ANPEPERAP2GPR84
SCHEMBL6552177 0.91 GPR84 (0.47) TSHRALDH1A1ANPEPERAP2GPR84
SCHEMBL963273 0.91 GPR84 (0.47) TSHRALDH1A1ANPEPERAP2GPR84
SCHEMBL965268 0.91 GPR84 (0.47) TSHRALDH1A1ANPEPERAP2GPR84
SCHEMBL966172 0.91 GPR84 (0.47) TSHRALDH1A1ANPEPERAP2GPR84
SCHEMBL18768856 0.91 TSHR (0.44) TSHRALDH1A1CYP3A4ANPEPERAP2
SCHEMBL19921560 0.91 ALDH1A1 (0.41) TSHRALDH1A1CYP3A4ANPEPERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11851390-B2 Reaction of glycoladehyde TAMINCO BVBA 2023-12-26 US disclosed
US-20210301217-A1 LUBRICATING COMPOSITION AND METHOD OF FORMATION RELATING THERETO IDEMITSU KOSAN Ltd. (JP) 2021-09-30 US disclosed
US-20210139410-A1 REACTION OF GLYCOLADEHYDE TAMINCO BVBA (BE) 2021-05-13 US disclosed
EP-3774717-A1 REACTION OF GLYCOLALDEHYDE TAMINCO BVBA (BE) 2021-02-17 EP disclosed
CN-111971269-A Reaction of glycolaldehyde 塔明克公司 2020-11-20 CN disclosed
EP-3290401-B1 N-SUBSTITUTED ACYCLIC ETHYLENE DIAMINES TAMINCO BVBA (BE) 2020-09-23 EP disclosed
WO-2019193117-A1 REACTION OF GLYCOLALDEHYDE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2019-10-10 WO disclosed
EP-3290401-A1 N-SUBSTITUTED ACYCLIC ETHYLENE DIAMINES Taminco bvba (BE) 2018-03-07 EP disclosed
EP-2280057-B2 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO (JP) 2016-11-23 EP disclosed
US-9321981-B2 Lubricating oil composition for internal combustion engine IDEMITSU KOSAN CO., LTD. (JP) 2016-04-26 US disclosed
EP-2280057-B1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO (JP) 2013-09-11 EP disclosed
CN-101184830-B Lubricating oil composition IDEMITSU KOSAN CO 2013-03-13 CN disclosed
EP-2280057-A1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE Idemitsu Kosan Co., Ltd. (JP) 2011-02-02 EP disclosed
US-20110021393-A1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO., LTD. (JP) 2011-01-27 US disclosed
US-7820599-B2 Lubricating oil composition IDEMITSU KOSAN CO., LTD. (JP) 2010-10-26 US disclosed
US-20090082233-A1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2009-03-26 US disclosed
CN-101184830-A Lubricating oil composition IDEMITSU KOSAN CO (JP) 2008-05-21 CN disclosed
EP-0978511-B1 N,N'-disubstituted N-(2-hydroxyalkyl)-Ureas BAYER AG (DE) 2003-10-22 EP disclosed
US-6177494-B1 HYDROLYSIS PROTECTION AGENTS IN PLASTICS CONTAINING ESTER GROUPS. BAYER AKTIENGESELLSCHAFT (DE) 2001-01-23 US disclosed
EP-0978511-A2 N,N'-disubstituted N-(2-hydroxyalkyl)-Ureas Bayer Aktiengesellschaft (DE) 2000-02-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11851390-B2 Reaction of glycoladehyde ADH1A, ADH1C, GRHPR TSHR 3008/4885ALDH1A1 26/4885CYP3A4 453/4885
US-20210139410-A1 REACTION OF GLYCOLADEHYDE ADH1A, ADH1C, GRHPR TSHR 3008/4885ALDH1A1 26/4885CYP3A4 453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.