Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SFRP1 | Q8N474 | 9/20 | 0.37 |
| ▸ | WNT3 | P56703 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9661599 | 0.85 | ALDH1A1 (0.42) | ALDH1A1NPSR1HRH4KMT2APOLB | |
| SCHEMBL9660134 | 0.85 | HRH4 (0.47) | ALDH1A1NPSR1HRH4KMT2ALMNA | |
| SCHEMBL9660737 | 0.73 | KMT2A (0.41) | ALDH1A1SFRP1WNT3HTR6KMT2A | |
| SCHEMBL9658808 | 0.73 | ALDH1A1 (0.37) | ALDH1A1SFRP1WNT3HTR6POLB | |
| SCHEMBL9658803 | 0.73 | ALDH1A1 (0.37) | ALDH1A1SFRP1WNT3HTR6POLB | |
| SCHEMBL9660900 | 0.71 | ALDH1A1 (0.42) | ALDH1A1NPSR1HRH4KMT2APOLB | |
| SCHEMBL10167004 | 0.70 | SMN1; SMN2 (0.43) | ALDH1A1SFRP1WNT3HRH4HTR6 | |
| SCHEMBL9690703 | 0.68 | ALDH1A1 (0.47) | ALDH1A1NPSR1POLBMAPTLMNA | |
| SCHEMBL9660750 | 0.67 | ALDH1A1 (0.44) | ALDH1A1NPSR1POLBLMNASMN1; SMN2 | |
| SCHEMBL10167002 | 0.67 | ESR1 (0.42) | ALDH1A1SFRP1WNT3HTR6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520274-A2 | 2-(-4-substituted-phenylhydrazino)-2-thiazoline and 2-(-4-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |