Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SFRP1 | Q8N474 | 7/20 | 0.39 |
| ▸ | WNT3 | P56703 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660140 | 0.85 | NPY1R (0.39) | KMT2ANPC1MEN1 | |
| SCHEMBL9661605 | 0.85 | KMT2A (0.38) | KMT2APOLBALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL9661610 | 0.77 | NPC1 (0.49) | KMT2APOLBALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL9658803 | 0.73 | ALDH1A1 (0.37) | SFRP1WNT3POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL9658808 | 0.73 | ALDH1A1 (0.37) | SFRP1WNT3POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL9660731 | 0.73 | ALDH1A1 (0.51) | KMT2ASFRP1WNT3POLBALDH1A1 | |
| SCHEMBL9660817 | 0.71 | KMT2A (0.41) | KMT2AALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL10841458 | 0.69 | KMT2A (0.51) | KMT2APOLBALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL9690711 | 0.68 | POLB (0.41) | KMT2APOLBALDH1A1NPC1ALOX15 | |
| SCHEMBL9660754 | 0.67 | KIF11 (0.41) | KMT2APOLBALDH1A1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520274-A2 | 2-(-4-substituted-phenylhydrazino)-2-thiazoline and 2-(-4-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |