Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SFRP1 | Q8N474 | 15/20 | 0.37 |
| ▸ | WNT3 | P56703 | 3/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9658803 | 1.00 | ALDH1A1 (0.37) | ALDH1A1SFRP1WNT3PTPN11HTR6 | |
| SCHEMBL9660700 | 0.85 | ALDH1A1 (0.35) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9660909 | 0.85 | KIF11 (0.39) | MAPTSMN1; SMN2 | |
| SCHEMBL9660906 | 0.85 | KIF11 (0.39) | MAPTSMN1; SMN2 | |
| SCHEMBL9660731 | 0.73 | ALDH1A1 (0.51) | ALDH1A1SFRP1WNT3HTR6POLB | |
| SCHEMBL9660737 | 0.73 | KMT2A (0.41) | ALDH1A1SFRP1WNT3HTR6POLB | |
| SCHEMBL9660787 | 0.71 | KMT2A (0.36) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9660795 | 0.71 | KMT2A (0.36) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9690036 | 0.68 | SMN1; SMN2 (0.39) | ALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL9661614 | 0.67 | LMNA (0.37) | ALDH1A1POLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520274-A2 | 2-(-4-substituted-phenylhydrazino)-2-thiazoline and 2-(-4-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |