Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9673132 | 0.86 | MAPT (0.57) | MAPTL3MBTL1MAPK1TDP1LTA4H | |
| Hydrochloric Acid SCHEMBL31644954 | 0.76 | LTA4H (0.49) | MAPTL3MBTL1MAPK1TDP1LTA4H | |
| SCHEMBL22219370 | 0.73 | MAPT (0.55) | MAPTL3MBTL1MAPK1TDP1LTA4H | |
| SCHEMBL3121966 | 0.71 | HTR1A (0.67) | MAPTL3MBTL1MAPK1TDP1KDM4E | |
| SCHEMBL6161980 | 0.70 | MAPT (0.53) | MAPTL3MBTL1MAPK1TDP1LTA4H | |
| SCHEMBL448079 | 0.70 | MAOB (0.57) | MAPTL3MBTL1MAPK1TDP1LTA4H | |
| SCHEMBL31139621 | 0.70 | MAPT (0.53) | MAPTL3MBTL1MAPK1TDP1LTA4H | |
| SCHEMBL2248786 | 0.70 | MAPT (0.53) | MAPTL3MBTL1MAPK1TDP1LTA4H | |
| SCHEMBL15583709 | 0.69 | MAOB (0.59) | MAPTL3MBTL1LTA4HCYP1A2CYP2C19 | |
| SCHEMBL7526430 | 0.69 | HTR1A (0.69) | MAPTL3MBTL1MAPK1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485026-A2 | Antimanic phenoxymethylene bisphosphonate derivatives | MERCK SHARP & DOHME LTD. (GB) | 1992-05-13 | — | — | EP | disclosed |