Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9664847 | 0.86 | MAPT (0.41) | MAPTALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL13520593 | 0.79 | ALDH1A1 (0.64) | MAPTALDH1A1KDM4ECYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL31644954 | 0.76 | LTA4H (0.49) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL18417242 | 0.76 | ALDH1A1 (0.45) | ALDH1A1LTA4HEPHX2HTR1ADRD2 | |
| SCHEMBL12849677 | 0.73 | CYP3A4 (1.00) | MAPTALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL22219370 | 0.73 | MAPT (0.55) | MAPTLTA4HLIPEMAPK1TDP1 | |
| SCHEMBL5630778 | 0.73 | HTR1A (0.56) | MAPTKDM4ELTA4HEPHX2LIPE | |
| SCHEMBL2180477 | 0.72 | CYP3A4 (0.67) | MAPTALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL10683333 | 0.71 | HTR1A (0.67) | MAPTALDH1A1KDM4ELTA4HEPHX2 | |
| SCHEMBL23883413 | 0.70 | TDP1 (0.44) | MAPTALDH1A1LTA4HLIPEMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485026-A2 | Antimanic phenoxymethylene bisphosphonate derivatives | MERCK SHARP & DOHME LTD. (GB) | 1992-05-13 | — | — | EP | disclosed |