Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1009755 | 0.76 | SLC6A4 (0.32) | MAOA | |
| SCHEMBL1009441 | 0.74 | SLC6A4 (0.32) | KDM4E | |
| SCHEMBL6812238 | 0.72 | DAO (0.39) | ALDH1A1MAOAMAOBKDM4ENPSR1 | |
| SCHEMBL6815167 | 0.70 | GRM5 (0.50) | ALDH1A1TSHRMAOAMAOBKDM4E | |
| SCHEMBL1009449 | 0.70 | CA2 (0.39) | KDM4E | |
| SCHEMBL6299483 | 0.70 | MAOA (0.46) | ALDH1A1MAOAMAOB | |
| SCHEMBL1009669 | 0.69 | — | — | |
| SCHEMBL1009488 | 0.69 | HTR7 (0.42) | — | |
| SCHEMBL6134799 | 0.69 | THRB (0.44) | MAOAMAOB | |
| SCHEMBL6815652 | 0.69 | SOD1 (0.40) | ALDH1A1TSHRMAOAMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267582-B1 | 2-CHLORO-4-( (CYANOMETHYL)THIO)PHENYL N-METHYL CARBAMATE | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-03-04 | — | — | EP | disclosed |
| EP-0267582-A2 | 2-Chloro-4-( (Cyanomethyl)thio)phenyl N-methyl carbamate | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-05-18 | — | — | EP | disclosed |